Pesquisa | Portal de Pesquisa da BVS

1.

Biomarkers of aging for the identification and evaluation of longevity interventions.

Moqri, Mahdi; Herzog, Chiara; Poganik, Jesse R; Justice, Jamie; Belsky, Daniel W; Higgins-Chen, Albert; Moskalev, Alexey; Fuellen, Georg; Cohen, Alan A; Bautmans, Ivan; Widschwendter, Martin; Ding, Jingzhong; Fleming, Alexander; Mannick, Joan; Han, Jing-Dong Jackie; Zhavoronkov, Alex; Barzilai, Nir; Kaeberlein, Matt; Cummings, Steven; Kennedy, Brian K; Ferrucci, Luigi; Horvath, Steve; Verdin, Eric; Maier, Andrea B; Snyder, Michael P; Sebastiano, Vittorio; Gladyshev, Vadim N.

Cell ; 186(18): 3758-3775, 2023 08 31.

Artigo em Inglês | MEDLINE | ID: mdl-37657418

2.

Ketogenic Diets Alter the Gut Microbiome Resulting in Decreased Intestinal Th17 Cells.

Ang, Qi Yan; Alexander, Margaret; Newman, John C; Tian, Yuan; Cai, Jingwei; Upadhyay, Vaibhav; Turnbaugh, Jessie A; Verdin, Eric; Hall, Kevin D; Leibel, Rudolph L; Ravussin, Eric; Rosenbaum, Michael; Patterson, Andrew D; Turnbaugh, Peter J.

Cell ; 181(6): 1263-1275.e16, 2020 06 11.

Artigo em Inglês | MEDLINE | ID: mdl-32437658

3.

Judith Campisi (1948-2024).

Verdin, Eric.

Cell ; 187(6): 1358-1359, 2024 Mar 14.

Artigo em Inglês | MEDLINE | ID: mdl-38490179

4.

NAD⁺ metabolism and its roles in cellular processes during ageing.

Covarrubias, Anthony J; Perrone, Rosalba; Grozio, Alessia; Verdin, Eric.

Nat Rev Mol Cell Biol ; 22(2): 119-141, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-33353981

5.

Anti-apoptotic Protein BIRC5 Maintains Survival of HIV-1-Infected CD4⁺ T Cells.

Kuo, Hsiao-Hsuan; Ahmad, Rushdy; Lee, Guinevere Q; Gao, Ce; Chen, Hsiao-Rong; Ouyang, Zhengyu; Szucs, Matthew J; Kim, Dhohyung; Tsibris, Athe; Chun, Tae-Wook; Battivelli, Emilie; Verdin, Eric; Rosenberg, Eric S; Carr, Steven A; Yu, Xu G; Lichterfeld, Mathias.

Immunity ; 48(6): 1183-1194.e5, 2018 06 19.

Artigo em Inglês | MEDLINE | ID: mdl-29802019

6.

50 years of protein acetylation: from gene regulation to epigenetics, metabolism and beyond.

Verdin, Eric; Ott, Melanie.

Nat Rev Mol Cell Biol ; 16(4): 258-64, 2015 04.

Artigo em Inglês | MEDLINE | ID: mdl-25549891

7.

Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation.

Wang, GuoXiao; Meyer, Jesse G; Cai, Weikang; Softic, Samir; Li, Mengyao Ella; Verdin, Eric; Newgard, Christopher; Schilling, Birgit; Kahn, C Ronald.

Mol Cell ; 74(4): 844-857.e7, 2019 05 16.

Artigo em Inglês | MEDLINE | ID: mdl-31000437

8.

The growing landscape of lysine acetylation links metabolism and cell signalling.

Choudhary, Chunaram; Weinert, Brian T; Nishida, Yuya; Verdin, Eric; Mann, Matthias.

Nat Rev Mol Cell Biol ; 15(8): 536-50, 2014 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-25053359

9.

The genome of a bunyavirus cannot be defined at the level of the viral particle but only at the scale of the viral population.

Yvon, Michel; German, Thomas L; Ullman, Diane E; Dasgupta, Ranjit; Parker, Maxwell H; Ben-Mahmoud, Sulley; Verdin, Eric; Gognalons, Patrick; Ancelin, Aurélie; Laï Kee Him, Joséphine; Girard, Justine; Vernerey, Marie-Stéphanie; Fernandez, Emmanuel; Filloux, Denis; Roumagnac, Philippe; Bron, Patrick; Michalakis, Yannis; Blanc, Stéphane.

Proc Natl Acad Sci U S A ; 120(48): e2309412120, 2023 Nov 28.

Artigo em Inglês | MEDLINE | ID: mdl-37983500

10.

MicroRNAs of the miR-17â¼92 family are critical regulators of T(FH) differentiation.

Kang, Seung Goo; Liu, Wen-Hsien; Lu, Peiwen; Jin, Hyun Yong; Lim, Hyung W; Shepherd, Jovan; Fremgen, Daniel; Verdin, Eric; Oldstone, Michael B A; Qi, Hai; Teijaro, John R; Xiao, Changchun.

Nat Immunol ; 14(8): 849-57, 2013 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-23812097

11.

From discoveries in ageing research to therapeutics for healthy ageing.

Campisi, Judith; Kapahi, Pankaj; Lithgow, Gordon J; Melov, Simon; Newman, John C; Verdin, Eric.

Nature ; 571(7764): 183-192, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-31292558

12.

A proposed unified mitotic chromosome architecture.

Sedat, John; McDonald, Angus; Kasler, Herbert; Verdin, Eric; Cang, Hu; Arigovindan, Muthuvel; Murre, Cornelis; Elbaum, Michael.

Proc Natl Acad Sci U S A ; 119(20): e2119107119, 2022 05 17.

Artigo em Inglês | MEDLINE | ID: mdl-35544689

13.

Neuronal SIRT3 Deletion Predisposes to Female-Specific Alterations in Cellular Metabolism, Memory, and Network Excitability.

Pearson-Smith, Jennifer N; Fulton, Ruth; Huynh, Christopher Q; Figueroa, Anna G; Huynh, Gia B; Liang, Li-Ping; Gano, Lindsey B; Michel, Cole R; Reisdorph, Nichole; Reisdorph, Richard; Fritz, Kristofer S; Verdin, Eric; Patel, Manisha.

J Neurosci ; 43(10): 1845-1857, 2023 03 08.

Artigo em Inglês | MEDLINE | ID: mdl-36759193

14.

SARS-CoV-2 protein ORF8 limits expression levels of Spike antigen and facilitates immune evasion of infected host cells.

Kim, Ik-Jung; Lee, Yong-Ho; Khalid, Mir M; Chen, Irene P; Zhang, Yini; Ott, Melanie; Verdin, Eric.

J Biol Chem ; 299(8): 104955, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37354973

15.

T cell stimulation remodels the latently HIV-1 infected cell population by differential activation of proviral chromatin.

Lindqvist, Birgitta; Jütte, Bianca B; Love, Luca; Assi, Wlaa; Roux, Julie; Sönnerborg, Anders; Tezil, Tugsan; Verdin, Eric; Svensson, J Peter.

PLoS Pathog ; 18(6): e1010555, 2022 06.

Artigo em Inglês | MEDLINE | ID: mdl-35666761

16.

SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein.

Walter, Marius; Chen, Irene P; Vallejo-Gracia, Albert; Kim, Ik-Jung; Bielska, Olga; Lam, Victor L; Hayashi, Jennifer M; Cruz, Andrew; Shah, Samah; Soveg, Frank W; Gross, John D; Krogan, Nevan J; Jerome, Keith R; Schilling, Birgit; Ott, Melanie; Verdin, Eric.

PLoS Pathog ; 18(9): e1010811, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-36095012

17.

Biological characterization of Physostegia chlorotic mottle virus, an emergent virus infecting vegetables in diversified production systems.

Temple, Coline; Blouin, Arnaud G; Boezen, Dieke; Botermans, Marleen; Durant, Laurena; De Jonghe, Kris; de Koning, Pier; Goedefroit, Thomas; Minet, Laurent; Steyer, Stephan; Verdin, Eric; Zwart, Mark; Massart, Sebastien.

Phytopathology ; 2024 Apr 22.

Artigo em Inglês | MEDLINE | ID: mdl-38648112

18.

In-depth analysis of the Sirtuin 5-regulated mouse brain malonylome and succinylome using library-free data-independent acquisitions.

Bons, Joanna; Rose, Jacob; Zhang, Ran; Burton, Jordan B; Carrico, Christopher; Verdin, Eric; Schilling, Birgit.

Proteomics ; 23(3-4): e2100371, 2023 02.

Artigo em Inglês | MEDLINE | ID: mdl-36479818

19.

NAD⁺ Repletion Reverses Heart Failure With Preserved Ejection Fraction.

Tong, Dan; Schiattarella, Gabriele G; Jiang, Nan; Altamirano, Francisco; Szweda, Pamela A; Elnwasany, Abdallah; Lee, Dong I; Yoo, Heesoo; Kass, David A; Szweda, Luke I; Lavandero, Sergio; Verdin, Eric; Gillette, Thomas G; Hill, Joseph A.

Circ Res ; 128(11): 1629-1641, 2021 05 28.

Artigo em Inglês | MEDLINE | ID: mdl-33882692

20.

SIRT5 Regulates both Cytosolic and Mitochondrial Protein Malonylation with Glycolysis as a Major Target.

Nishida, Yuya; Rardin, Matthew J; Carrico, Chris; He, Wenjuan; Sahu, Alexandria K; Gut, Philipp; Najjar, Rami; Fitch, Mark; Hellerstein, Marc; Gibson, Bradford W; Verdin, Eric.

Mol Cell ; 59(2): 321-32, 2015 Jul 16.

Artigo em Inglês | MEDLINE | ID: mdl-26073543

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